The HIST1H2AB Antibody (N-term) from MyBioSource.com is a Rabbit Polyclonal antibody to H2A clustered histone 4, H2A clustered histone 8, H2AC4, and H2AC8. This antibody recognizes Human, Mouse, Bovine, Chicken/Bird, Non-Human Primate, Xenopus/Amphibian, and Zebrafish/Fish antigen. The HIST1H2AB Antibody (N-term) has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. This structure consists of approximately 146 bp of DNA
wrapped around a nucleosome, an octamer composed of pairs of each
of the four core histones (H2A, H2B, H3, and H4). The chromatin
fiber is further compacted through the interaction of a linker
histone, H1, with the DNA between the nucleosomes to form higher
order chromatin structures. This gene is intronless and encodes a
member of the histone H2A family. Transcripts from this gene lack
polyA tails; instead, they contain a palindromic termination
element. This gene is found in the large histone gene cluster on
chromosome 6p22-p21.3